best website builder

Selected PUBLICATIONS

1. Young H*, Schramek D*, Adams R, Heller E, Keys BK, Wang P, Zheng D and Fuchs E. ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas. Elife. 2015 Nov 21;4. 

2. Grabner B, Schramek D, Mueller KM, Zwick RH, Penninger JM, Moriggl R, Sibilia M, Popper H, Eferl R, Casanova E. Disruption of STAT3 signaling promotes KRAS induced lung tumorigenesis. Nat Commun 2015 Mar 3. 3;6:6285

3. Schramek D, Segal JP, Beronja S, Heller E, Oristian D and Fuchs E. Direct In vivo RNAi screen unveils myosin lla as a tumor suppressor of aquamous cell carcinomas. Science 2014 Jan 17;343(6168):309-13. 

4. Rao S, Tortola L, Perlot T, Nitsch R, Novatchkova M, Frank L, Schramek D, Komnenovic V, Wirnsberger G, Sigl V, Aumayr K, Schmauss G, Fellner N, Pasierbek P, Soto S, Mizushima N, Kenner L, Kroemer G and Penninger JM. A dual role of autophagy in murine model of lung cancer. Nat Commun. 2014 Jan 20;5:3056.

5. Elling U, Taubenschmid J, Wirnsberger G, O'Malley R, Demers SP, Vanhaelen Q, Shukalyuk AI, Schramek D, Schnuetgen F, von Melchner H, Ecker JR, Stanford WL, Zuber J, Stark A and Penninger JM. Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. Cell Stem Cell. 2011 Dec 2;9(6):563.

6. Schramek D, Meixner A, Kotsinas A, Wada T, Zwick RH, Pospisilik JA, Neely GG, Gorgoulis VG and Penninger JM. The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression. Nature Genetics 2011 Mar;43(3):212-9. 

8. Schramek D and Penninger JM. The Many Roles of RANKL-RANK Signaling in Bone, Breast and Cancer. IBMS BoneKEy. 2011 May;8(5):237-56.

9. Schramek D, Sigl V, Penninger JM. RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis. Trends Endocrinol Metab. 2011 May;22(5):188-94.

10. Schramek D*, Leibbrandt A*, Sigl V, Kenner L, Pospisilik A, Lee H, Aliprantis A, Kiechl S, Willeit J, Ormandy C, Glimcher L, Pasparakis M, Schett G and Penninger JM. Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature 2010 Nov 4;468(7320):98. 

11. Pospisilik JA*, Schramek D*, Schnidar H, Cronin SJ, Nehme NT, Zhang X, Knauf C, Cani PD, Aumayr K, Todoric J, Bayer M, Haschemi A, Puviindran V, Tar K, Orthofer M, Neely GG, Dietzl G, Manoukian A, Funovics M, Prager G, Wagner O, Ferrandon D, Aberger F, Hui CC, Esterbauer H and Penninger JM. Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell 2010 Jan 8;140(1):148-60. 

12. Neely GG, Hess A, Costigan M, Keene AC, Goulas S, Langeslag M, Griffin RS, Belfer I, Dai F, Smith SB, Diatchenko L, Gupta V, Xia CP, Amann S, Kreitz S, Heindl-Erdmann C, Wolz S, Ly CV, Arora S, Sarangi R, Dan D, Novatchkova M, Rosenzweig M, Gibson DG, Truong D, Schramek D, Zoranovic T, Cronin SJ, Angjeli B, Brune K, Dietzl G, Maixner W, Meixner A, Thomas W, Pospisilik JA, Alenius M, Kress M, Subramaniam S, Garrity PA, Bellen HJ, Woolf CJ, Penninger JM. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell 2010 Nov 12;143(4):628-38. 

13. Cronin SJ, Nehme NT, Limmer S, Liegeois S, Pospisilik JA, Schramek D, Leibbrandt A, Simoes Rde M, Gruber S, Puc U, Ebersberger I, Neely GG, von Haeseler A, Ferrandon D and Penninger JM.Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection. Science 2009 Jul 17; 325(5938):340-3. 

14. Brummer T*, Schramek D*, Hayes VM, Bennett HL, Caldon CE, Musgrove EA and Daly RJ. Increased proliferation and altered growth factor dependency of human mammary epithelial cells overexpressing the Gab2 docking protein. J Biol Chem. 2006 Jan 6;281(1):626.